Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | AQP1 | P29972 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256879 | 0.82 | AQP1 (0.47) | HTR1AAQP1PARP1SLC6A4NOTUM | |
| SCHEMBL8258997 | 0.78 | HTR1A (0.38) | HTR1AAQP1PARP1NOTUMCDK2 | |
| SCHEMBL8254383 | 0.76 | CTNNB1 (0.39) | HTR1APARP1SLC6A4NOTUM | |
| SCHEMBL8248817 | 0.75 | AQP1 (0.38) | HTR1AAQP1PARP1NOTUM | |
| SCHEMBL8257870 | 0.73 | AQP1 (0.38) | HTR1AAQP1PARP1SLC6A4ACHE | |
| SCHEMBL8210298 | 0.73 | AQP1 (0.54) | AQP1MAPK10MAPK14SLC6A4HTR2C | |
| SCHEMBL8248843 | 0.72 | LMNA (0.36) | HTR1APARP1CDK2CDK9ACHE | |
| SCHEMBL8248841 | 0.71 | XDH (0.34) | HTR1AAQP1PARP1NOTUM | |
| SCHEMBL8256849 | 0.70 | PARP1 (0.34) | HTR1APARP1NOTUMCDK2CDK9 | |
| SCHEMBL15319473 | 0.69 | PARP1 (0.41) | HTR1APARP1NOTUMHTR2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116165-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |