Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970993 | 0.88 | DGAT1 (0.36) | SMN1; SMN2KCNN4KDM4EDGAT1LMNA | |
| SCHEMBL27858824 | 0.82 | MEN1 (0.38) | SMN1; SMN2HIF1AKCNN4DGAT1SRC | |
| SCHEMBL609386 | 0.78 | DGAT1 (0.39) | SMN1; SMN2HIF1AKDM4EDGAT1 | |
| SCHEMBL28721112 | 0.78 | DGAT1 (0.39) | SMN1; SMN2HIF1AKDM4EDGAT1 | |
| SCHEMBL6009380 | 0.78 | ALOX15 (0.39) | SMN1; SMN2KDM4ELMNA | |
| SCHEMBL1066622 | 0.78 | DGAT1 (0.39) | SMN1; SMN2HIF1AKDM4EDGAT1 | |
| SCHEMBL27858821 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2HIF1AKCNN4DGAT1LMNA | |
| SCHEMBL27738859 | 0.78 | ARG2 (0.34) | SMN1; SMN2HIF1AKCNN4DGAT1 | |
| SCHEMBL8861395 | 0.78 | ARG1 (0.35) | SMN1; SMN2HIF1AKDM4E | |
| SCHEMBL825611 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2HIF1AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048444-A1 | IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS | BECTON DICKINSON AND COMPANY (US) | 1997-12-24 | — | — | WO | claimed |
| WO-1995014683-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-06-01 | — | — | WO | claimed |