SCHEMBL825689

SCHEMBL825689

CC(NC1CCNC1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.41
EPHX1 P07099 2/20 0.39
CPN1 P15169 2/20 0.37
CPB2 Q96IY4 2/20 0.37
SLC6A1 P30531 4/20 0.36
GABRA5 P31644 3/20 0.36
GABRB2 P47870 3/20 0.36
SLC6A11 P48066 3/20 0.36
SLC6A13 Q9NSD5 3/20 0.36
SLC6A12 P48065 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRA4 P48169 2/20 0.36
POLB P06746 1/20 0.36
GABRR1 P24046 1/20 0.36
TSHR P16473 2/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825809 1.00 KCNH2 (0.41) KCNH2EPHX1CPN1CPB2SLC6A1
SCHEMBL31109672 1.00 KCNH2 (0.41) KCNH2EPHX1CPN1CPB2SLC6A1
SCHEMBL6371477 0.89 CPN1 (0.45) EPHX1CPN1CPB2SLC6A1SLC6A11
SCHEMBL384885 0.89 CPN1 (0.45) EPHX1CPN1CPB2SLC6A1SLC6A11
SCHEMBL384884 0.89 CPN1 (0.45) EPHX1CPN1CPB2SLC6A1SLC6A11
SCHEMBL6371199 0.89 EPHX1 (0.47) EPHX1CPN1CPB2GABRA5GABRB2
SCHEMBL384923 0.89 EPHX1 (0.47) EPHX1CPN1CPB2GABRA5GABRB2
SCHEMBL384924 0.89 EPHX1 (0.47) EPHX1CPN1CPB2GABRA5GABRB2
SCHEMBL1801065 0.84 KCNH2 (0.40) KCNH2EPHX1SLC6A1GABRA5GABRB2
SCHEMBL1801069 0.84 KCNH2 (0.40) KCNH2EPHX1SLC6A1GABRA5GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883721-B2 Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof MCGILL UNIVERSITY (CA) 2014-11-11 US claimed
US-20120135918-A1 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF MCGILL UNIVERSITY (CA) 2012-05-31 US claimed
US-20250354176-A1 TARGETING PEPTIDE TO DELIVER A COMPOUND TO OOCYTES PENN STATE RES FOUND (US) 2025-11-20 US disclosed
EP-4622996-A1 CONTROL OF NANOCAGE SELF-ASSEMBLY King's College London (GB) 2025-10-01 EP disclosed
US-12391962-B2 Targeting peptide to deliver a compound to oocytes THE PENN STATE RESEARCH FOUNDATION (PA) 2025-08-19 US disclosed
US-20250206802-A1 MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-06-26 US disclosed
WO-2024110757-A1 CONTROL OF NANOCAGE SELF-ASSEMBLY KING'S COLLEGE LONDON (GB) 2024-05-30 WO disclosed
US-11976382-B2 Nucleic acid based biosensor and methods thereof BOISE STATE UNIVERSITY (US) 2024-05-07 US disclosed
US-20240117006-A1 MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-04-11 US disclosed
US-11807677-B2 Microbe-binding molecules and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-11-07 US disclosed
US-11701429-B2 Targeted drug delivery through affinity based linkers Akamara Therapeutics, Inc. (US) 2023-07-18 US disclosed
WO-2013071049-A1 GRAMICIDIN A MUTANTS THAT FUNCTION AS ANTIBIOTICS WITH IMPROVED SOLUBILITY AND REDUCED TOXICITY TRUSTEES OF BOSTON COLLEGE (US) 2013-05-16 WO disclosed
WO-2013071079-A1 LIN28/LET-7 CRYSTAL STRUCTURES, PURIFICATION PROTOCOLS, AND MOLECULAR PROBES SUITABLE FOR SCREENING ASSAYS AND THERAPEUTICS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-05-16 WO disclosed
EP-2582715-A2 GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF The Administrators of the Tulane Educational Fund (US) 2013-04-24 EP disclosed
US-20130064895-A1 Amphiphilic Peptides and Peptide Particles PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-03-14 US disclosed
WO-2013028843-A1 PEPTIDE NANOPARTICLES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-02-28 WO disclosed
WO-2012177986-A2 CONJUGATE-BASED ANTIFUNGAL AND ANTIBACTERIAL PRODRUGS VYOME BIOSCIENCES (IN) 2012-12-27 WO disclosed
US-20120135918-A1 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF MCGILL UNIVERSITY (CA) 2012-05-31 US disclosed
WO-2011159917-A2 GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2011-12-22 WO disclosed
WO-2010132580-A2 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2010-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240117006-A1 MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF ITGA2B, ITGB1, ITGA1 KCNH2 4148/4885EPHX1 2760/4885CPN1 696/4885
US-20120135918-A1 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF GHSR, GIPR, GHRHR KCNH2 4290/4885EPHX1 4130/4885CPN1 582/4885
US-11701429-B2 Targeted drug delivery through affinity based linkers ABCG2, FCGR2A, ABCB1 KCNH2 4179/4885EPHX1 1009/4885CPN1 1765/4885
US-20250206802-A1 MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF ITGA2B, ITGB1, ITGA1 KCNH2 4148/4885EPHX1 2760/4885CPN1 696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.