Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6371477 | 1.00 | CPN1 (0.45) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL384884 | 1.00 | CPN1 (0.45) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL825689 | 0.89 | KCNH2 (0.41) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL31109672 | 0.89 | KCNH2 (0.41) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL825809 | 0.89 | KCNH2 (0.41) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL1798175 | 0.85 | KDM4E (0.44) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL1798169 | 0.85 | KDM4E (0.44) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL919280 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2ACYP2D6KDM4EMAPT | |
| SCHEMBL157944 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2KMT2ACYP2D6KDM4EMAPT | |
| SCHEMBL147119 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2ACYP2D6KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007055578-A1 | CYCLIC ANTIMICROBIAL PEPTIDES DERIVED FROM LACTOFERRIN | LEIDS UNIVERSITAIR MEDISCH CENTRUM (NL) | 2007-05-18 | — | — | WO | claimed |
| US-20050119190-A1 | Inhibitors of the blood-clotting factor xa, production thereof and use of the same | CURACYTE AG (DE) | 2005-06-02 | — | — | US | claimed |
| EP-1483285-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | Curacyte AG (DE) | 2004-12-08 | — | — | EP | claimed |
| WO-2003076457-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2003-09-18 | — | — | WO | claimed |
| US-9012603-B2 | Peptides that block the binding of IgG to FcRn | BIOGEN IDEC HEMOPHILIA INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-8906844-B2 | Immunomodulatory peptides | BIOGEN IDEC HEMOPHILIA INC. (US) | 2014-12-09 | — | — | US | disclosed |
| WO-2012149018-A1 | MER TYROSINE KINASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2012-11-01 | — | — | WO | disclosed |
| US-8101186-B2 | Peptides that block the binding of IgG to FcRn | SYNTONIX PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110230639-A1 | IMMUNOMODULATORY PEPTIDES | SYNTONIX PHARMACEUTICALS INC. (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110059889-A1 | PEPTIDES THAT BLOCK THE BINDING OF IgG TO FcRn | SYNTONIX PHARMACEUTICALS, INC. | 2011-03-10 | — | — | US | disclosed |
| EP-2203471-A2 | IMMUNOMODULATORY PEPTIDES | SYNTONIX PHARMACEUTICALS, INC. (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009020867-A2 | IMMUNOMODULATORY PEPTIDES | SYNTONIX PHARMACEUTICALS, INC. (US) | 2009-02-12 | — | — | WO | disclosed |
| US-6057314-A | ANTICOAGULANTS | BIOCHEM PHARMA INC. (CA) | 2000-05-02 | — | — | US | disclosed |
| EP-0846120-A1 | LOW MOLECULAR WEIGHT BICYCLIC-AREA TYPE THROMBIN INHIBITORS | BIOCHEM PHARMA INC (CA) | 1998-06-10 | — | — | EP | disclosed |
| EP-0846125-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1998009987-A1 | LACTAM INHIBITORS OF THROMBIN | BIOCHEM PHARMA, INC. (CA) | 1998-03-12 | — | — | WO | disclosed |
| EP-0802916-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC (CA) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996040743-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996037497-A1 | LOW MOLECULAR WEIGHT BICYCLIC-UREA TYPE THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-11-28 | — | — | WO | disclosed |
| WO-1996019483-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059889-A1 | PEPTIDES THAT BLOCK THE BINDING OF IgG TO FcRn | FCGRT, FCGR3B, FCGR1A | CPN1 199/4885CPB2 217/4885SLC6A1 3995/4885 |
| US-20050119190-A1 | Inhibitors of the blood-clotting factor xa, production thereof and use of the same | SERPINC1, TFPI, F11 | CPN1 432/4885CPB2 31/4885SLC6A1 3927/4885 |
| US-20110230639-A1 | IMMUNOMODULATORY PEPTIDES | FCGRT, FCGR3B, FCGR2A | CPN1 548/4885CPB2 479/4885SLC6A1 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.