SCHEMBL8258487

SCHEMBL8258487

O=C(N[C@H](Cc1ccc(F)cc1)C(=O)O)OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR34 Q9UPC5 2/20 0.63
ITGB3 P05106 8/20 0.63
ITGA2B P08514 8/20 0.63
ALDH1A1 P00352 2/20 0.62
TACR1 P25103 2/20 0.60
CTSL P07711 1/20 0.58
CTSB P07858 1/20 0.58
CTSS P25774 1/20 0.58
CTSK P43235 1/20 0.58
ALOX15 P16050 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10722503 1.00 GPR34 (0.63) GPR34ITGB3ITGA2BALDH1A1TACR1
SCHEMBL2511842 1.00 GPR34 (0.63) GPR34ITGB3ITGA2BALDH1A1TACR1
SCHEMBL7291131 1.00 GPR34 (0.63) GPR34ITGB3ITGA2BALDH1A1TACR1
SCHEMBL10724240 0.95 TACR1 (0.61) GPR34ITGB3ITGA2BALDH1A1TACR1
SCHEMBL10724885 0.95 TACR1 (0.61) GPR34ITGB3ITGA2BALDH1A1TACR1
SCHEMBL10724242 0.95 TACR1 (0.61) GPR34ITGB3ITGA2BALDH1A1TACR1
SCHEMBL10724879 0.95 TACR1 (0.61) GPR34ITGB3ITGA2BALDH1A1TACR1
SCHEMBL5396021 0.93 GPR34 (0.76) GPR34ITGB3ITGA2B
SCHEMBL5396470 0.93 GPR34 (0.76) GPR34ITGB3ITGA2B
SCHEMBL219151 0.92 TACR1 (0.68) ITGB3ITGA2BALDH1A1TACR1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-20070185060-A1 Boronic acid thrombin inhibitors TRIGEN LIMITED (GB) 2007-08-09 US disclosed
US-20070185060-A1 Boronic acid thrombin inhibitors TRIGEN LIMITED (GB) 2007-08-09 US disclosed
US-20050282757-A1 Peptide boronic acid compounds useful in anticoagulation TRIGEN LIMITED 2005-12-22 US disclosed
US-20050282757-A1 Peptide boronic acid compounds useful in anticoagulation TRIGEN LIMITED 2005-12-22 US disclosed
WO-2005084687-A2 BORONIC ACID THROMBIN INHIBITORS TRIGEN LIMITED (GB) 2005-09-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282757-A1 Peptide boronic acid compounds useful in anticoagulation SERPINC1, HABP2, F11 GPR34 2853/4885ITGB3 1478/4885ITGA2B 1324/4885
US-20070185060-A1 Boronic acid thrombin inhibitors F2, ECE1, BCAT1 GPR34 4282/4885ITGB3 1337/4885ITGA2B 534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.