Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825518 | 0.83 | MAPT (0.47) | MAPTNPSR1ALDH1A1L3MBTL1HTT | |
| SCHEMBL935506 | 0.77 | MAPT (0.49) | MAPTNPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL3708781 | 0.76 | MAPT (0.38) | MAPTNPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL10359187 | 0.74 | MAPT (0.44) | MAPTNPSR1ALDH1A1L3MBTL1HTT | |
| SCHEMBL23521388 | 0.73 | L3MBTL1 (0.39) | MAPTNPSR1L3MBTL1GAAHTT | |
| SCHEMBL27297982 | 0.69 | MAPT (0.40) | MAPTNPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28638892 | 0.69 | THRB (0.42) | LMNA | |
| SCHEMBL8523802 | 0.67 | MAPT (0.40) | MAPTNPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL703186 | 0.66 | THRB (0.40) | LMNA | |
| SCHEMBL704750 | 0.66 | PKM (0.33) | L3MBTL1LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157970-A1 | SILYLATED POLYURETHANES | Huntsman International LLC (US) | 2017-04-26 | — | — | EP | claimed |
| WO-2015193146-A1 | SILYLATED POLYURETHANES | HUNTSMAN INTERNATIONAL LLC (US) | 2015-12-23 | — | — | WO | claimed |
| WO-2020239746-A1 | COMPOSITION COMPRISING SILYLATED POLYMER | HUNTSMAN INTERNATIONAL LLC (US) | 2020-12-03 | — | — | WO | disclosed |
| EP-2582737-A1 | ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS | Huntsman International LLC (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011161011-A1 | ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS | HUNTSMAN INTERNATIONAL LLC (US) | 2011-12-29 | — | — | WO | disclosed |
| WO-2005019296-A1 | THERMOPLASTIC POLYURETHANE CONTAINING SILANE GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-03 | — | — | WO | disclosed |