Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | PYGL | P06737 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260020 | 0.91 | PYGL (0.57) | PYGL | |
| SCHEMBL22534020 | 0.85 | MAOB (0.60) | — | |
| SCHEMBL3603913 | 0.80 | ALOX15 (0.56) | ALOX15PYGL | |
| SCHEMBL3603024 | 0.80 | ALOX15 (0.56) | ALOX15PYGL | |
| SCHEMBL3603019 | 0.80 | ALOX15 (0.56) | ALOX15PYGL | |
| SCHEMBL18767312 | 0.77 | MAOB (0.67) | — | |
| SCHEMBL8255991 | 0.76 | SMYD3 (0.58) | CHRM1 | |
| SCHEMBL22373838 | 0.76 | SCN9A (0.48) | CHRM1 | |
| SCHEMBL8251721 | 0.76 | CHRNA7 (0.47) | CHRM1 | |
| SCHEMBL3605105 | 0.76 | ALOX15 (0.54) | ALOX15PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| WO-2006114401-A2 | NOVEL CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | WO | disclosed |