Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5782120 | 0.99 | MAPT (0.51) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL8970512 | 0.80 | KMT2A (0.47) | MAPTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL8971555 | 0.78 | KMT2A (0.48) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| Bromide SCHEMBL9243928 | 0.78 | ALDH1A1 (0.47) | MAPTKMT2AMEN1ALDH1A1HTT | |
| Iodide SCHEMBL26666896 | 0.78 | ALDH1A1 (0.46) | MAPTRAB9AALDH1A1LMNAPOLB | |
| Iodide SCHEMBL30690005 | 0.78 | ALDH1A1 (0.46) | MAPTRAB9AALDH1A1LMNAPOLB | |
| SCHEMBL5944038 | 0.77 | MAPT (0.60) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| Nitrobenzene SCHEMBL8971309 | 0.77 | HPGD (0.48) | MAPTKMT2ARAB9AALDH1A1MAPK1 | |
| Dinitrophenylene SCHEMBL27988648 | 0.73 | MAPT (0.55) | MAPTKMT2AMEN1ALDH1A1GLO1 | |
| Dinitrophenylene SCHEMBL27790604 | 0.73 | GLO1 (0.55) | MAPTKMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097570-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | NEUROSEARCH A/S | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097570-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | GABRA1, GABRA2, GABRA4 | MAPT 906/4885KMT2A 1116/4885MEN1 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.