Biotin

Biotin

SCHEMBL826595

O=C(O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 1.00
MEN1 O00255 1/20 1.00
ABL1 P00519 1/20 1.00
LMNA P02545 1/20 1.00
PKM P14618 1/20 1.00
IDE P14735 1/20 1.00
MAPK1 P28482 1/20 1.00
KMT2A Q03164 1/20 1.00
RIN1 Q13671 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
HLCS P50747 6/20 0.69
CA12 O43570 7/20 0.56
CA1 P00915 7/20 0.56
CA2 P00918 7/20 0.56
CA9 Q16790 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL5376391 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL36572 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9841217 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL410686 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL59420 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL21981206 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3384633 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747409-A2 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS Hackensack Meridian Health, Inc. (US) 2026-05-27 EP claimed
US-20260103737-A1 ENZYMATIC METHODS TO GENERATE HIGH YIELDS OF SEQUENCE SPECIFIC RNA OLIGONUCLEOTIDES WITH EXTREME PRECISION UNIV MASSACHUSETTS (US) 2026-04-16 US claimed
US-12325873-B2 Enzymatic methods to generate high yields of sequence specific RNA oligonucleotides with extreme precision UNIVERSITY OF MASSACHUSETTS (US) 2025-06-10 US claimed
CN-119753176-A Composition and method for detecting pseudomonas fragicide based on CRISPR/Cas12a 浙江省海洋水产研究所 2025-04-04 CN claimed
WO-2025019709-A2 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS HACKENSACK MERIDIAN HEALTH, INC. (US) 2025-01-23 WO claimed
US-20240410022-A1 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS HACKENSACK MERIDIAN HEALTH, INC. (US) 2024-12-12 US claimed
US-20240344056-A1 IMPROVED METHOD OF SEQUENCING LIBRARY PREPARATION FOR SHORT DNA SOMAGENICS INC (US) 2024-10-17 US claimed
CN-115029417-B Slit type Raman enhanced nano-tag, estradiol detection system, kit and application 首都医科大学 2024-09-24 CN claimed
US-11999994-B2 Methods for production and quantification of unique molecular identifier-labeled beads INTEGRATED DNA TECHNOLOGIES, INC. (US) 2024-06-04 US claimed
EP-4278005-A1 METHODS FOR PRODUCTION AND QUANTIFICATION OF UNIQUE MOLECULAR IDENTIFIER-LABELED BEADS Integrated DNA Technologies, Inc. (US) 2023-11-22 EP claimed
CN-115896321-A CrRNA for rapidly detecting Karenia mikimotoi and primer pair thereof 闽江学院 2023-04-04 CN claimed
US-11578348-B2 Enzymatic methods to generate high yields of sequence specific rna with extreme precision THE UNIVERSITY OF MASSACHUSETTS (US) 2023-02-14 US claimed
WO-2022256560-A1 IMPROVED METHOD OF SEQUENCING LIBRARY PREPARATION FOR SHORT DNA SOMAGENICS, INC. (US) 2022-12-08 WO claimed
EP-3669370-B1 METHOD FOR DETERMINATION OF CELLULAR MRNA GOVERNING COUNCIL UNIV TORONTO (CA) 2022-10-05 EP claimed
CN-115029417-A Gap type Raman enhanced nano-label, estradiol detection system, kit and application 首都医科大学 2022-09-09 CN claimed
CN-114774410-A Primer, kit and detection method for detecting verticillium dahliae based on RPA-CRISPR/Cas12a 西北农林科技大学 2022-07-22 CN claimed
WO-2022155282-A1 METHODS FOR PRODUCTION AND QUANTIFICATION OF UNIQUE MOLECULAR IDENTIFIER-LABELED BEADS INTEGRATED DNA TECHNOLOGIES, INC. (US) 2022-07-21 WO claimed
US-20220220545-A1 METHODS FOR PRODUCTION AND QUANTIFICATION OF UNIQUE MOLECULAR IDENTIFIER-LABELED BEADS INTEGRATED DNA TECHNOLOGIES, INC. 2022-07-14 US claimed
US-11332778-B2 Methods and systems for nucleic acid amplification GENAPSYS, INC. (US) 2022-05-17 US claimed
EP-2467142-B1 2-(Pyrimidin-5-yl)-thiopyrimidine derivatives as Hsp70 and Hsc70 modulators for the treatment of proliferative disorders SLOAN KETTERING INST CANCER (US) 2016-09-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103737-A1 ENZYMATIC METHODS TO GENERATE HIGH YIELDS OF SEQUENCE SPECIFIC RNA OLIGONUCLEOTIDES WITH EXTREME PRECISION RNGTT, POLRMT, POLM TDP1 144/4885MEN1 4880/4885ABL1 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.