Biotin

Biotin

SCHEMBL3384633

O=C(O)CCCCC1SC[C@@H]2NC(=O)N[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 1.00
MEN1 O00255 1/20 1.00
ABL1 P00519 1/20 1.00
LMNA P02545 1/20 1.00
PKM P14618 1/20 1.00
IDE P14735 1/20 1.00
MAPK1 P28482 1/20 1.00
KMT2A Q03164 1/20 1.00
RIN1 Q13671 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
HLCS P50747 6/20 0.69
CA12 O43570 7/20 0.56
CA1 P00915 7/20 0.56
CA2 P00918 7/20 0.56
CA9 Q16790 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL826595 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5376391 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL36572 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9841217 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL410686 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL59420 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL21981206 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023154852-A1 ANTIBODY BARCODED BEADS AND USES THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-08-17 WO claimed
EP-3727351-A1 ENGINEERED EXTRACELLULAR VESICLES FOR ENHANCED TISSUE DELIVERY Cedars-Sinai Medical Center (US) 2020-10-28 EP claimed
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US disclosed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US disclosed
US-12391930-B2 Polymerase compositions and kits, and methods of using and making the same Life Technologies Corporation (US) 2025-08-19 US disclosed
US-12338465-B2 Polymerase compositions, methods of making and using same Life Technologies Corporation (US) 2025-06-24 US disclosed
US-20250163391-A1 NUCLEOTIDE TRANSIENT BINDING FOR SEQUENCING METHODS LIFE TECHNOLOGIES CORP (US) 2025-05-22 US disclosed
US-12215383-B2 Polymerase compositions and methods of making and using same Life Technologies Corporation (US) 2025-02-04 US disclosed
US-12163188-B2 Polymerase compositions and methods Life Technologies Corporation (US) 2024-12-10 US disclosed
US-12152256-B2 Nucleotide transient binding for sequencing methods Life Technologies Corporation (US) 2024-11-26 US disclosed
US-20080182971-A1 PEPTIDE DERIVATIVES, AND THEIR USE FOR THE SYNTHESIS OF SILICON-BASED COMPOSITE MATERIALS GENENCOR INTERNATIONAL, INC. (US) 2008-07-31 US disclosed
US-7361731-B2 Peptide derivatives, and their use for the synthesis of silicon-based composite materials GENENCOR INTERNATIONAL, INC. (US) 2008-04-22 US disclosed
US-7279285-B2 Method of reversibly disrupting a conjugate comprising a biotin compound and a biotin-binding compound MAGNETIC BIOSOLUTIONS AB (SE) 2007-10-09 US disclosed
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal SDG, INC. 2007-09-20 US disclosed
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal SDG, INC. 2007-09-20 US disclosed
WO-2005081622-A1 METHODS AND COMPOSITIONS FOR THE DETECTION OF NITRIC OXIDE PHARMACIA & UPJOHN COMPANY LLC (US) 2005-09-09 WO disclosed
US-20040077024-A1 Method of reversibly disrupting a conjugate comprising a biotin compound and a biotin compound NORDIAG AB (SE) 2004-04-22 US disclosed
US-20020155157-A1 Compositions and methods for polynucleotide delivery THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION 2002-10-24 US disclosed
US-6368813-B1 FLAVORS OF AVADIN ANTIBIOTICS THE TRUSTEES OF BOSTON UNIVERSITY 2002-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal HAVCR2, IFNAR1, MSR1 TDP1 4728/4885MEN1 4097/4885ABL1 2979/4885
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 TDP1 4819/4885MEN1 966/4885ABL1 4375/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 TDP1 4755/4885MEN1 2415/4885ABL1 4626/4885
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL GPR119, INSR, FABP1 TDP1 4833/4885MEN1 2073/4885ABL1 4576/4885
US-12163188-B2 Polymerase compositions and methods POLN, POLI, POLRMT TDP1 88/4885MEN1 4479/4885ABL1 1051/4885
US-20040077024-A1 Method of reversibly disrupting a conjugate comprising a biotin compound and a biotin compound BTD, HLCS, MMAB TDP1 3392/4885MEN1 2726/4885ABL1 2156/4885
US-20020155157-A1 Compositions and methods for polynucleotide delivery POLN, NCLN, APOB TDP1 905/4885MEN1 4306/4885ABL1 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.