Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29300382 | 0.81 | TERT (0.52) | MCHR1HDAC3HDAC6NCOR2TERT | |
| SCHEMBL16213688 | 0.81 | ALDH1A1 (0.53) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| SCHEMBL8234410 | 0.80 | HDAC3 (0.61) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| SCHEMBL29300416 | 0.80 | NPC1 (0.51) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| SCHEMBL8269125 | 0.80 | HDAC3 (0.53) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| SCHEMBL8122188 | 0.79 | SMN1; SMN2 (0.63) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11545112 | 0.79 | NAAA (0.57) | HDAC3HDAC6NCOR2NPC1RAB9A | |
| SCHEMBL20031964 | 0.79 | HDAC3 (0.59) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| SCHEMBL8269305 | 0.78 | MAPK1 (0.55) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| SCHEMBL29300418 | 0.78 | TERT (0.49) | MCHR1HDAC3HDAC6NCOR2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | TPSAB1, TPSB2, TPSD1 | MCHR1 2386/4885HDAC3 3559/4885HDAC6 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.