Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29069314 | 0.72 | TRPA1 (0.31) | — | |
| SCHEMBL1325645 | 0.71 | TDP1 (0.36) | ALDH1A1 | |
| SCHEMBL5614009 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL1325499 | 0.69 | DPP4 (0.39) | — | |
| SCHEMBL15302890 | 0.67 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL15301796 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL15302595 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL15302723 | 0.67 | TAAR1 (0.33) | ALDH1A1 | |
| SCHEMBL15302680 | 0.67 | TDP1 (0.33) | — | |
| SCHEMBL12815293 | 0.67 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650263-B1 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | MINNESOTA MINING MFG GMBH (DE) | 2013-10-23 | — | — | EP | disclosed |
| US-8143362-B2 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100331444-A1 | COMPOSITION CONTAINING UNSATURATED SILICONE COMPOUNDS, DENTAL MATERIALS CONTAINING THEM AND USE THEREOF | 3M ESPE AG (A WHOLLY-OWNED SUBSIDUARY OF 3M COMPANY) | 2010-12-30 | — | — | US | disclosed |
| US-7807730-B2 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | 3M ESPE AG (DE) | 2010-10-05 | — | — | US | disclosed |
| US-20060111464-A1 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | 3M DEUTSCHLAND GMBH (DE) | 2006-05-25 | — | — | US | disclosed |
| EP-1652889-A1 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | 3M Espe AG (DE) | 2006-05-03 | — | — | EP | disclosed |
| EP-1650263-A1 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | 3M Espe AG (DE) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331444-A1 | COMPOSITION CONTAINING UNSATURATED SILICONE COMPOUNDS, DENTAL MATERIALS CONTAINING THEM AND USE THEREOF | SMCHD1, CAD, ESD | ALDH1A1 1550/4885 |
| US-20060111464-A1 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | CAD, SMCHD1, SUPT16H | ALDH1A1 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.