Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | HRAS | P01112 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221812 | 0.90 | CHRM4 (0.38) | HPGDSDGAT2RPS6KB1 | |
| SCHEMBL14452908 | 0.90 | CHRM4 (0.38) | HPGDSDGAT2RPS6KB1 | |
| SCHEMBL8273768 | 0.87 | HPGDS (0.38) | HPGDSALDH1A1L3MBTL1HDAC3HDAC1 | |
| SCHEMBL8275469 | 0.79 | ADAM17 (0.36) | HPGDSALDH1A1HDAC1HDAC2DGAT2 | |
| SCHEMBL8217550 | 0.77 | ADAM17 (0.44) | HPGDSRPS6KB1 | |
| SCHEMBL14452920 | 0.76 | CHRM4 (0.41) | DPP8DPP9 | |
| SCHEMBL8221551 | 0.76 | CHRM4 (0.41) | DPP8DPP9 | |
| SCHEMBL8276118 | 0.73 | ADAM17 (0.43) | ALDH1A1L3MBTL1DPP8DPP9DPP7 | |
| SCHEMBL8274407 | 0.73 | ADAM17 (0.43) | ALDH1A1L3MBTL1DPP8DPP9DPP7 | |
| SCHEMBL8275285 | 0.72 | NAMPT (0.42) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |