Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275148 | 0.84 | KMO (0.48) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8275150 | 0.83 | ROCK2 (0.48) | GAAALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL8219836 | 0.78 | GAA (0.46) | GAAALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL14494457 | 0.77 | RIPK1 (0.47) | GAATSHRHPGDMEN1KMT2A | |
| SCHEMBL8414743 | 0.76 | KMO (0.56) | GAAALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL8275132 | 0.76 | MC4R (0.43) | — | |
| SCHEMBL8275146 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRKMT2AROCK2 | |
| SCHEMBL10723960 | 0.72 | HPGD (0.68) | GAAALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL8220141 | 0.71 | MBTD1 (0.49) | GAAALDH1A1TSHRHPGDMEN1 | |
| SCHEMBL13504020 | 0.69 | ALDH1A1 (0.74) | GAAALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |