Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168688 | 1.00 | MEN1 (0.45) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL13278820 | 1.00 | MEN1 (0.45) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL30158137 | 1.00 | MEN1 (0.45) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL29765420 | 0.92 | HIF1A (0.52) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL483559 | 0.92 | HIF1A (0.52) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL30354029 | 0.92 | HIF1A (0.52) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL123529 | 0.92 | HIF1A (0.52) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL828172 | 0.92 | HIF1A (0.52) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL14141835 | 0.92 | HIF1A (0.52) | MEN1KMT2APPARGPPARAHIF1A | |
| SCHEMBL123530 | 0.92 | HIF1A (0.52) | MEN1KMT2APPARGPPARAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013050324-A1 | COMBINATION, CONTAINING 4-PHENYLBUTYRIC ACID (4-PBA) OR A SALT THEREOF (COMPONENT (A)) AND ONE OR MORE SELECTED ADDITIONAL AGRONOMICALLY ACTIVE COMPOUNDS (COMPONENT(S) (B)), THAT REDUCES ABIOTIC PLANT STRESS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-11 | — | — | WO | claimed |
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |
| US-10435372-B2 | Use of phenylpyrazolin-3-carboxylates for improving plant yield | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-10-08 | — | — | US | disclosed |
| EP-2964023-B1 | USE OF N-(2-METHOXYBENZOYL)-4-[METHYLAMINOCARBONYL)AMINO]BENZENESULFONAMIDE IN COMBINATION WITH AN INSECTICIDE OR FUNGICIDE FOR IMPROVING PLANT YIELD | BAYER CROPSCIENCE AG (DE) | 2019-08-07 | — | — | EP | disclosed |
| US-20190233369-A1 | USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-08-01 | — | — | US | disclosed |
| US-10301257-B2 | Use of acylsulfonamides for improving plant yield | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| US-9963431-B2 | Use of quinoline derivatives for improving plant yield | BAYER CROPSCIENCE AG (DE) | 2018-05-08 | — | — | US | disclosed |
| US-9949485-B2 | Use of acylsulfonamides for improving plant yield | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20170332640-A1 | USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| US-20170156327-A1 | USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-06-08 | — | — | US | disclosed |
| EP-2471363-A1 | Use of aryl-, heteroaryl- and benzylsulfonamide carboxylic acids, -carboxylic acid esters, -carboxylic acid amides and -carbonitriles and/or its salts for increasing stress tolerance in plants | Bayer CropScience AG (DE) | 2012-07-04 | — | — | EP | disclosed |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20120077677-A1 | Use of 4-phenylbutyric acid and/or salts thereof for enhancing stress tolerance in plants | BAYER CROPSCIENCE AG (DE) | 2012-03-29 | — | — | US | disclosed |
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| US-20110294664-A1 | USE OF DERIVATIVES OF (1-CYANOCYCLOPROPYL)PHENYLPHOSPHINIC ACID, ESTERS THEREOF AND/OR SALTS THEREOF FOR ENHANCING TOLERANCE IN PLANTS TO ABIOTIC STRESS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2011124553-A2 | USE OF DERIVATIVES OF THE (1-CYANOCYCLOPROPYL)PHENYLPHOSPHINIC ACID, THE ESTERS THEREOF AND/OR THE SALTS THEREOF FOR ENHANCING THE TOLERANCE OF PLANTS TO ABIOTIC STRESS | BAYER CROPSCIENCE AG (DE) | 2011-10-13 | — | — | WO | disclosed |
| US-20110230350-A1 | ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | US | disclosed |
| WO-2011113861-A2 | ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011107504-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2011-09-09 | — | — | WO | disclosed |
| US-20110218103-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435372-B2 | Use of phenylpyrazolin-3-carboxylates for improving plant yield | CBR3, HRH4, HRH3 | MEN1 1053/4885KMT2A 3863/4885PPARG 3963/4885 |
| US-20190233369-A1 | USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD | ARSA, ACSS2, NAT1 | MEN1 3168/4885KMT2A 901/4885PPARG 2692/4885 |
| US-20110230350-A1 | ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS | STS, ARSA, TST | MEN1 4795/4885KMT2A 1543/4885PPARG 906/4885 |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | DHPS, FDPS, DPYD | MEN1 3414/4885KMT2A 3719/4885PPARG 1211/4885 |
| US-20110218103-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles | BOLA2; BOLA2B, ARFIP2, PFAS | MEN1 4324/4885KMT2A 1466/4885PPARG 854/4885 |
| US-20120077677-A1 | Use of 4-phenylbutyric acid and/or salts thereof for enhancing stress tolerance in plants | PAH, ABAT, HPD | MEN1 4860/4885KMT2A 3276/4885PPARG 328/4885 |
| US-20110294664-A1 | USE OF DERIVATIVES OF (1-CYANOCYCLOPROPYL)PHENYLPHOSPHINIC ACID, ESTERS THEREOF AND/OR SALTS THEREOF FOR ENHANCING TOLERANCE IN PLANTS TO ABIOTIC STRESS | PPA1, PHOSPHO1, PHYKPL | MEN1 3985/4885KMT2A 4494/4885PPARG 2240/4885 |
| US-20170332640-A1 | USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD | PAOX, BROX, CYP4Z1 | MEN1 4878/4885KMT2A 2668/4885PPARG 276/4885 |
| US-10301257-B2 | Use of acylsulfonamides for improving plant yield | ARSA, ACSS2, NAT1 | MEN1 3168/4885KMT2A 901/4885PPARG 2692/4885 |
| US-20170156327-A1 | USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD | CBR3, HRH4, HRH3 | MEN1 1053/4885KMT2A 3863/4885PPARG 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.