Sugi Predict

Sugi Predict / Compounds / SCHEMBL168688

SCHEMBL168688

SCHEMBL168688

CCO/N=C(/C(=O)NC)c1ccccc1CO/N=C(\C)c1cccc(C(F)(F)F)c1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ PPARG P37231 4/20 0.43
▸ PPARA Q07869 3/20 0.43
▸ HIF1A Q16665 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ TP53 P04637 2/20 0.39
▸ RXFP1 Q9HBX9 2/20 0.39
▸ DDR1 Q08345 1/20 0.39
▸ LMNA P02545 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ ABCB1 P08183 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168689 1.00 MEN1 (0.45) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL13278820 1.00 MEN1 (0.45) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL30158137 1.00 MEN1 (0.45) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL29765420 0.92 HIF1A (0.52) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL483559 0.92 HIF1A (0.52) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL30354029 0.92 HIF1A (0.52) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL123529 0.92 HIF1A (0.52) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL828172 0.92 HIF1A (0.52) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL14141835 0.92 HIF1A (0.52) MEN1KMT2APPARGPPARAHIF1A
SCHEMBL123530 0.92 HIF1A (0.52) MEN1KMT2APPARGPPARAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013050324-A1 COMBINATION, CONTAINING 4-PHENYLBUTYRIC ACID (4-PBA) OR A SALT THEREOF (COMPONENT (A)) AND ONE OR MORE SELECTED ADDITIONAL AGRONOMICALLY ACTIVE COMPOUNDS (COMPONENT(S) (B)), THAT REDUCES ABIOTIC PLANT STRESS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-04-11 — — WO claimed
WO-2022268520-A1 USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-12-29 — — WO disclosed
US-10435372-B2 Use of phenylpyrazolin-3-carboxylates for improving plant yield BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-10-08 — — US disclosed
EP-2964023-B1 USE OF N-(2-METHOXYBENZOYL)-4-[METHYLAMINOCARBONYL)AMINO]BENZENESULFONAMIDE IN COMBINATION WITH AN INSECTICIDE OR FUNGICIDE FOR IMPROVING PLANT YIELD BAYER CROPSCIENCE AG (DE) 2019-08-07 — — EP disclosed
US-20190233369-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-08-01 — — US disclosed
US-10301257-B2 Use of acylsulfonamides for improving plant yield BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-05-28 — — US disclosed
US-9963431-B2 Use of quinoline derivatives for improving plant yield BAYER CROPSCIENCE AG (DE) 2018-05-08 — — US disclosed
US-9949485-B2 Use of acylsulfonamides for improving plant yield BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-24 — — US disclosed
US-20170332640-A1 USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-11-23 — — US disclosed
US-20170156327-A1 USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-06-08 — — US disclosed
EP-2471363-A1 Use of aryl-, heteroaryl- and benzylsulfonamide carboxylic acids, -carboxylic acid esters, -carboxylic acid amides and -carbonitriles and/or its salts for increasing stress tolerance in plants Bayer CropScience AG (DE) 2012-07-04 — — EP disclosed
US-20120157306-A1 Substituted Fused Pyrimidinones and Dihydropyrimidinones BAYER CROPSCIENCE AG (DE) 2012-06-21 — — US disclosed
US-20120077677-A1 Use of 4-phenylbutyric acid and/or salts thereof for enhancing stress tolerance in plants BAYER CROPSCIENCE AG (DE) 2012-03-29 — — US disclosed
WO-2012028578-A1 SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES BAYER CROPSCIENCE AG (DE) 2012-03-08 — — WO disclosed
US-20110294664-A1 USE OF DERIVATIVES OF (1-CYANOCYCLOPROPYL)PHENYLPHOSPHINIC ACID, ESTERS THEREOF AND/OR SALTS THEREOF FOR ENHANCING TOLERANCE IN PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2011-12-01 — — US disclosed
WO-2011124553-A2 USE OF DERIVATIVES OF THE (1-CYANOCYCLOPROPYL)PHENYLPHOSPHINIC ACID, THE ESTERS THEREOF AND/OR THE SALTS THEREOF FOR ENHANCING THE TOLERANCE OF PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2011-10-13 — — WO disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 — — US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 — — WO disclosed
WO-2011107504-A1 FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2011-09-09 — — WO disclosed
US-20110218103-A1 Fluoroalkyl-substituted 2-amidobenzimidazoles BAYER CROPSCIENCE AG (DE) 2011-09-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435372-B2 Use of phenylpyrazolin-3-carboxylates for improving plant yield CBR3, HRH4, HRH3 MEN1 1053/4885KMT2A 3863/4885PPARG 3963/4885
US-20190233369-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD ARSA, ACSS2, NAT1 MEN1 3168/4885KMT2A 901/4885PPARG 2692/4885
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST MEN1 4795/4885KMT2A 1543/4885PPARG 906/4885
US-20120157306-A1 Substituted Fused Pyrimidinones and Dihydropyrimidinones DHPS, FDPS, DPYD MEN1 3414/4885KMT2A 3719/4885PPARG 1211/4885
US-20110218103-A1 Fluoroalkyl-substituted 2-amidobenzimidazoles BOLA2; BOLA2B, ARFIP2, PFAS MEN1 4324/4885KMT2A 1466/4885PPARG 854/4885
US-20120077677-A1 Use of 4-phenylbutyric acid and/or salts thereof for enhancing stress tolerance in plants PAH, ABAT, HPD MEN1 4860/4885KMT2A 3276/4885PPARG 328/4885
US-20110294664-A1 USE OF DERIVATIVES OF (1-CYANOCYCLOPROPYL)PHENYLPHOSPHINIC ACID, ESTERS THEREOF AND/OR SALTS THEREOF FOR ENHANCING TOLERANCE IN PLANTS TO ABIOTIC STRESS PPA1, PHOSPHO1, PHYKPL MEN1 3985/4885KMT2A 4494/4885PPARG 2240/4885
US-20170332640-A1 USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD PAOX, BROX, CYP4Z1 MEN1 4878/4885KMT2A 2668/4885PPARG 276/4885
US-10301257-B2 Use of acylsulfonamides for improving plant yield ARSA, ACSS2, NAT1 MEN1 3168/4885KMT2A 901/4885PPARG 2692/4885
US-20170156327-A1 USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD CBR3, HRH4, HRH3 MEN1 1053/4885KMT2A 3863/4885PPARG 3963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.