Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286587 | 0.92 | L3MBTL1 (0.42) | KMT2AL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL2907636 | 0.86 | PDE4A (0.41) | KMT2APIK3CDPIK3R1PIK3CAL3MBTL1 | |
| SCHEMBL8284814 | 0.86 | CTSL (0.41) | PDE4APDE4BPDE4CPDE4DCTSL | |
| SCHEMBL8284045 | 0.84 | KMT2A (0.41) | KMT2AL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL8285836 | 0.82 | GPBAR1 (0.38) | CTSLGPBAR1TP53MAPTCHRNB2 | |
| SCHEMBL8286591 | 0.82 | CHRNB2 (0.38) | KMT2AL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL8284774 | 0.81 | SLC6A4 (0.35) | PDE4APDE4BPDE4CPDE4DCTSL | |
| SCHEMBL2908560 | 0.78 | L3MBTL1 (0.43) | KMT2AL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL8284052 | 0.76 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL8284049 | 0.74 | PTGER2 (0.38) | PDE4APDE4BPDE4CPDE4DGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061458-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |