Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286587 | 0.92 | L3MBTL1 (0.42) | KMT2ATDP1POLBMEN1LMNA | |
| SCHEMBL2906139 | 0.86 | KMT2A (0.41) | KMT2ATDP1POLBNPC1MEN1 | |
| SCHEMBL8285836 | 0.85 | GPBAR1 (0.38) | GPBAR1 | |
| SCHEMBL8284814 | 0.84 | CTSL (0.41) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8284044 | 0.84 | KMT2A (0.40) | KMT2ATDP1POLBPDE4APDE4B | |
| SCHEMBL8284774 | 0.83 | SLC6A4 (0.35) | PDE4APDE4BPDE4CPDE4DGPBAR1 | |
| SCHEMBL8284052 | 0.80 | PDE4A (0.38) | NPSR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8286591 | 0.79 | CHRNB2 (0.38) | KMT2APOLBMEN1PDE4APDE4B | |
| SCHEMBL2908560 | 0.78 | L3MBTL1 (0.43) | KMT2ATDP1POLBMEN1LMNA | |
| SCHEMBL8285678 | 0.75 | GRM2 (0.38) | KMT2AMEN1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061458-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |