Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469742 | 1.00 | CTSS (0.47) | CTSSCTSKPTGIRFFAR1PPARD | |
| SCHEMBL8284726 | 0.87 | PTGIR (0.49) | CTSSCTSKPTGIRTNK2MRGPRX4 | |
| SCHEMBL14451472 | 0.87 | PTGIR (0.49) | CTSSCTSKPTGIRTNK2MRGPRX4 | |
| SCHEMBL5516232 | 0.84 | PTGIR (0.50) | PTGIRKAT6A | |
| SCHEMBL5516229 | 0.84 | PTGIR (0.50) | PTGIRKAT6A | |
| SCHEMBL8284719 | 0.81 | CCKBR (0.48) | CTSSCTSKPTGIRTNK2MRGPRX4 | |
| SCHEMBL8393648 | 0.81 | LMNA (0.58) | F13A1TGM2TGM1 | |
| SCHEMBL7770012 | 0.79 | ALDH1A1 (0.50) | TNK2F13A1TGM2TGM1 | |
| SCHEMBL14451405 | 0.79 | LMNA (0.54) | PTGIRF13A1TGM2TGM1 | |
| SCHEMBL7766510 | 0.78 | TGM2 (0.55) | GRIN2BF13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | PFIZER, INC. | 2007-07-19 | — | — | US | disclosed |
| WO-2005080317-A2 | THERAPEUTIC AMIDE DERIVATIVES | PFIZER JAPAN, INC. (JP) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | GRIN1, GRIN2B, GRIN3A | CTSS 3404/4885CTSK 3117/4885PTGIR 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.