Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871846 | 0.84 | PDE11A (0.49) | LMNASMN1; SMN2MAPTPDE11ATP53 | |
| SCHEMBL8286456 | 0.84 | L3MBTL1 (0.44) | L3MBTL1TAAR1LMNASMN1; SMN2MAPT | |
| SCHEMBL8287872 | 0.77 | MAT2A (0.47) | L3MBTL1TAAR1LMNASMN1; SMN2MAPT | |
| SCHEMBL8287801 | 0.77 | ALDH1A2 (0.37) | L3MBTL1TAAR1SMN1; SMN2MAPTPDE11A | |
| SCHEMBL8285301 | 0.76 | L3MBTL1 (0.41) | L3MBTL1TAAR1LMNASMN1; SMN2MAPT | |
| SCHEMBL8287198 | 0.76 | L3MBTL1 (0.41) | L3MBTL1TAAR1LMNASMN1; SMN2MAPT | |
| SCHEMBL8287868 | 0.74 | PDE11A (0.47) | L3MBTL1TAAR1LMNAMAPTPDE11A | |
| SCHEMBL5871658 | 0.74 | PDE11A (0.48) | LMNASMN1; SMN2MAPTPDE11AKDM4E | |
| SCHEMBL8285163 | 0.74 | POLB (0.50) | LMNASMN1; SMN2MAPTPDE11ATP53 | |
| SCHEMBL8286378 | 0.73 | PDE11A (0.49) | LMNAMAPTPDE11ATP53RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005091857-A2 | 1,6-NAPHTHYRIDINE AND 1,8-NAPHTHYRIDINE DERIVATIVES AND THEIR USE TO TREAT DIABETES AND RELATED DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |
| WO-2003027112-A1 | 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |