Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289937 | 0.83 | GRM2 (0.49) | NPC1RAB9AHTTMAPTL3MBTL1 | |
| SCHEMBL4417838 | 0.81 | FAAH (0.42) | PDE10ANPC1RAB9ADGAT1HTT | |
| SCHEMBL8288813 | 0.79 | P2RX3 (0.43) | NPC1RAB9AHTTMAPTL3MBTL1 | |
| SCHEMBL6253989 | 0.77 | LDHA (0.44) | NPC1RAB9AHTTKMT2AGAA | |
| SCHEMBL8287911 | 0.77 | MAOA (0.42) | NPC1RAB9AHTTMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6259317 | 0.77 | LDHA (0.44) | NPC1RAB9AHTTKMT2AGAA | |
| SCHEMBL6267930 | 0.75 | PDE10A (0.38) | PDE10ANPC1RAB9ACXCR6ALDH1A1 | |
| SCHEMBL8278308 | 0.74 | HTT (0.48) | NPC1RAB9AHTTMAPTL3MBTL1 | |
| SCHEMBL4417835 | 0.73 | FAAH (0.49) | PDE10ANPC1RAB9ADGAT1HTT | |
| SCHEMBL8290091 | 0.73 | HTT (0.43) | NPC1RAB9ADGAT1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058317-A1 | GLYCINE TRANSPORTER-1 INHIBIRORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |