Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932114 | 0.78 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AHPGDUSP2 | |
| SCHEMBL8284613 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EKMT2AHPGDUSP2 | |
| SCHEMBL8283679 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL14003034 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL12226857 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL12226859 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL12226856 | 0.71 | HDAC1 (0.41) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL12226858 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL4284545 | 0.69 | KDM4E (0.37) | ALDH1A1KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL8284750 | 0.69 | KDM4E (0.38) | ALDH1A1KDM4EKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723136-B1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2011-03-09 | — | — | EP | disclosed |
| WO-2005058873-A1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |