Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288001 | 0.86 | LMNA (0.40) | KDM4EALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL8285627 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL14003034 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL8283679 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL4863283 | 0.84 | MAPT (0.45) | KDM4EALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL4281670 | 0.84 | KDM4E (0.36) | KDM4EALDH1A1SMN1; SMN2HSD17B10USP2 | |
| SCHEMBL8284750 | 0.83 | KDM4E (0.38) | KDM4EALDH1A1LMNASMN1; SMN2PCSK9 | |
| SCHEMBL4286685 | 0.82 | TSPO (0.36) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL1495304 | 0.80 | KCNH2 (0.38) | CYP3A4TLR7LMNASMN1; SMN2USP2 | |
| SCHEMBL13932114 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711485-B1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2009-05-13 | — | — | EP | disclosed |
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
| WO-2005058870-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | NQO2, NOX3, NOX1 | KDM4E 3254/4885ALDH1A1 2090/4885CYP3A4 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.