Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281670 | 0.90 | KDM4E (0.36) | KDM4EUSP2HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL8283679 | 0.85 | KDM4E (0.39) | KDM4EUSP2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL14003034 | 0.85 | KDM4E (0.39) | KDM4EUSP2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL4284545 | 0.83 | KDM4E (0.37) | KDM4EUSP2HPGDHSD17B10LMNA | |
| SCHEMBL8285627 | 0.81 | KDM4E (0.33) | KDM4EUSP2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL13932114 | 0.80 | KDM4E (0.43) | KDM4EUSP2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL4286685 | 0.79 | TSPO (0.36) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL4288001 | 0.78 | LMNA (0.40) | KDM4EHPGDHSD17B10LMNAALDH1A1 | |
| SCHEMBL8284613 | 0.78 | KDM4E (0.41) | KDM4EUSP2HPGDHSD17B10LMNA | |
| SCHEMBL4280686 | 0.77 | P2RX3 (0.34) | KDM4EALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058870-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |