SCHEMBL829003

SCHEMBL829003

CC(C)(C)OC(=O)N1CCOS1(=O)=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
RECQL P46063 1/20 0.39
CTSK P43235 1/20 0.36
HSD11B1 P28845 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
HPGD P15428 1/20 0.34
EPHX1 P07099 1/20 0.33
NR1H2 P55055 1/20 0.32
PREP P48147 1/20 0.31
EPHX2 P34913 1/20 0.31
FAAH O00519 1/20 0.31
CTSD P07339 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16617849 0.90 USP2 (0.45) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL31500356 0.82 USP2 (0.34) USP2SMN1; SMN2RECQL
SCHEMBL17190805 0.81 USP2 (0.42) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL1978328 0.75 USP2 (0.40) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL1979622 0.75 USP2 (0.40) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL1983350 0.75 USP2 (0.40) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL17113045 0.73 USP2 (0.36) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL1978663 0.70 USP2 (0.39) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL2980172 0.70 USP2 (0.39) USP2SMN1; SMN2RECQLCTSKHSD11B1
SCHEMBL2904445 0.70 USP2 (0.39) USP2SMN1; SMN2RECQLCTSKHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300012-A Method for preparing 2-methoxy ethylamine hydrochloride 上海睿瓦科技有限公司 2021-02-02 CN claimed
CN-122059906-A Compounds for inhibiting PTPN proteins and uses thereof 艾斯拓康生物医药(天津)有限公司 2026-05-19 CN disclosed
CN-122010871-A Compounds for inhibiting PTPN proteins and uses thereof 艾斯拓康生物医药(天津)有限公司 2026-05-12 CN disclosed
US-12606541-B2 PPARg modulators and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-04-21 US disclosed
US-12577227-B2 WDR5 inhibitors and modulators VANDERBILT UNIVERSITY (US) 2026-03-17 US disclosed
US-12552775-B2 Compounds and uses thereof FOGHORN THERAPEUTICS INC. (US) 2026-02-17 US disclosed
CN-121537623-A Synthesis method of single molecular weight amino tert-butyloxycarbonyl polyethylene glycol derivative 武汉软件工程职业学院(武汉开放大学) 2026-02-17 CN disclosed
EP-4688778-A1 1H-PYRROLO[2,3-B]PYRIDIN-4-YL]-2-OXOPYRROLIDINE-3-CARBONITRILE DERIVATIVES AS TYROSINE KINASE 2 (TYK2) INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES Biogen MA Inc. (US) 2026-02-11 EP disclosed
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF BIOGEN MA INC (US) 2026-01-29 US disclosed
EP-3681875-B1 CYCLIC PEPTIDE ANTIBIOTICS HOFFMANN LA ROCHE (CH) 2026-01-14 EP disclosed
EP-1325008-A1 PIPERAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-07-09 EP disclosed
US-6583134-B2 Tricyclic aza-indolyl derivatives substituted with ethylamine group is useful for treating central nervous system disorder,cardiovascular disorder, gastrointestinal disorders, diabetes insipidus, and particularly useful for obesity HOFFMAN-LA ROCHE INC. 2003-06-24 US disclosed
WO-2003037327-A1 N-SUBSTITUTED PYRROLIDIN DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS F. HOFFMANN-LA-ROCHE AG (CH) 2003-05-08 WO disclosed
EP-1274711-A1 NEW AZA-INDOLYL DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-01-15 EP disclosed
US-20020169163-A1 Piperazine derivatives HOFFMAN-LA ROCHE INC. 2002-11-14 US disclosed
WO-2002072584-A2 TETRAHYDRO-PYRAZINO (1,2-A) INDOLES FOR THE TREATMENT OF CENTRAL NERVOUS DISORDERS F. HOFFMANN-LA ROCHE AG (CH) 2002-09-19 WO disclosed
US-20020035110-A1 Anti-obesity 1,2,3,4,10,10-a-hexahydropy razino [1,2-a] indoles VERNALIS RESEARCH LIMITED, A BRITISH COMPANY (GB) 2002-03-21 US disclosed
WO-2002010169-A1 PIPERAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2002-02-07 WO disclosed
US-20010025039-A1 Aza- indolyl derivatives for treating obesity HOFFMANN-LA ROCHE INC. 2001-09-27 US disclosed
WO-2001066548-A1 NEW AZA-INDOLYL DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2001-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552775-B2 Compounds and uses thereof SMARCC1, SMARCC2, CHD1 USP2 2985/4885SMN1; SMN2 238/4885RECQL 531/4885
US-20010025039-A1 Aza- indolyl derivatives for treating obesity GPR119, GIPR, INMT USP2 2439/4885SMN1; SMN2 1512/4885RECQL 1140/4885
US-20020169163-A1 Piperazine derivatives GPR119, SLC5A2, DPP4 USP2 1060/4885SMN1; SMN2 491/4885RECQL 2852/4885
US-20020035110-A1 Anti-obesity 1,2,3,4,10,10-a-hexahydropy razino [1,2-a] indoles GPR119, HTR1D, HTR1A USP2 1275/4885SMN1; SMN2 1242/4885RECQL 1949/4885
US-12577227-B2 WDR5 inhibitors and modulators WDR1, WDR5, WDR3 USP2 2161/4885SMN1; SMN2 2571/4885RECQL 1493/4885
US-12606541-B2 PPARg modulators and methods of use PPARG, PPARA, PPARD USP2 4057/4885SMN1; SMN2 3901/4885RECQL 1351/4885
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF TYK2, ERBB2, ROS1 USP2 2410/4885SMN1; SMN2 1972/4885RECQL 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.