Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509963 | 0.84 | AHR (0.44) | ESR1ESR2HSP90AA1AHR | |
| SCHEMBL5509193 | 0.78 | ESR1 (0.37) | ESR1ESR2HSP90AA1AHR | |
| SCHEMBL5514165 | 0.76 | ESR1 (0.40) | ESR1ESR2HSP90AA1 | |
| SCHEMBL5505902 | 0.74 | ESR1 (0.37) | ESR1ESR2HSP90AA1AHR | |
| SCHEMBL8290795 | 0.69 | ESR1 (0.41) | ESR1ESR2HSP90AA1 | |
| SCHEMBL12879280 | 0.69 | ESR1 (0.42) | ESR1ESR2HSP90AA1 | |
| SCHEMBL5513632 | 0.69 | FAAH (0.49) | ESR1ESR2HSP90AA1AHR | |
| SCHEMBL1836503 | 0.69 | ALDH1A1 (0.49) | ESR1ESR2HSP90AA1AHR | |
| SCHEMBL11443734 | 0.68 | ESR1 (0.43) | ESR1ESR2HSP90AA1 | |
| SCHEMBL5508112 | 0.64 | ESR1 (0.63) | ESR1ESR2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066143-A2 | BENZO[D]ISOXAZOL-3-OL DAAO INHIBITORS | SEPRACOR INC. (US) | 2005-07-21 | — | — | WO | disclosed |