Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | PLG | P00747 | 1/20 | 0.63 |
| ▸ | PLAU | P00749 | 1/20 | 0.63 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.63 |
| ▸ | KLK1 | P06870 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.63 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21206956 | 0.92 | PLAU (0.55) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL397225 | 0.81 | CES2 (0.60) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL23890384 | 0.80 | HPGD (0.58) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL21206942 | 0.78 | ESR1 (0.50) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL43058 | 0.77 | ALDH1A1 (0.71) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL3399368 | 0.77 | F2 (0.63) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL30999689 | 0.77 | CES2 (0.56) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL3370031 | 0.77 | PLAU (1.00) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL29521283 | 0.77 | CES2 (0.56) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL29941688 | 0.77 | PLAU (1.00) | F2PLGPLAUKLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355705-A1 | DISCOVERY OF YEATS2 YEATS DOMAIN INHIBITORS AS NOVEL ANTI-CANCER AGENTS | THE UNIVERSITY OF HONG KONG (CN) | 2023-11-09 | — | — | US | disclosed |
| US-11370740-B2 | Method for producing ester group-containing compound | DIC CORPORATION (JP) | 2022-06-28 | — | — | US | disclosed |
| US-10919870-B2 | Polymerizable compound and optically anisotropic body | DIC CORPORATION (JP) | 2021-02-16 | — | — | US | disclosed |
| US-20200199453-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | US | disclosed |
| EP-2892525-B1 | METHODS OF TREATING MUSCULAR DYSTROPHY | UNIV NEVADA RENO (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-2788359-B1 | COMPOSITION AND METHOD FOR NEUROPEPTIDE S RECEPTOR (NPSR) ANTAGONISTS | RES TRIANGLE INST (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-1636218-B1 | THIAZOLYLPIPERIDINE DERIVATIVES AS MTP INHIBITORS | MERCK PATENT GMBH (DE) | 2009-03-25 | — | — | EP | disclosed |
| WO-2005037779-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005037257-A2 | NOVEL ALANYL-AMINO PEPTIDASE INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370740-B2 | Method for producing ester group-containing compound | COASY, TAF5, TAF9 | F2 345/4885PLG 2742/4885PLAU 3316/4885 |
| US-10919870-B2 | Polymerizable compound and optically anisotropic body | ZYX, ZW10, DPY30 | F2 308/4885PLG 370/4885PLAU 502/4885 |
| US-20230355705-A1 | DISCOVERY OF YEATS2 YEATS DOMAIN INHIBITORS AS NOVEL ANTI-CANCER AGENTS | YEATS2, YEATS4, KNTC1 | F2 4877/4885PLG 4148/4885PLAU 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.