Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343137 | 0.78 | ALOX12 (0.67) | ALOX12ALDH1A1HPGDMAOAGAA | |
| SCHEMBL8294741 | 0.76 | HDAC1 (0.49) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8711125 | 0.73 | ALOX12 (0.59) | ALOX12ALDH1A1HPGDMAOAGAA | |
| SCHEMBL8294749 | 0.72 | HDAC1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1366507 | 0.70 | HDAC1 (0.67) | GAAMEN1KMT2AEPHX2HDAC3 | |
| SCHEMBL5998068 | 0.69 | MEN1 (0.73) | ALDH1A1GAAMEN1KMT2AEPHX2 | |
| SCHEMBL6438376 | 0.68 | EPHX2 (0.80) | MAOAGAAMEN1KMT2AEPHX2 | |
| SCHEMBL18459797 | 0.68 | L3MBTL1 (0.65) | ALDH1A1MAOAGAAMEN1KMT2A | |
| SCHEMBL6436358 | 0.68 | EPHX2 (0.80) | MAOAGAAMEN1KMT2AEPHX2 | |
| SCHEMBL6436792 | 0.68 | EPHX2 (0.80) | MAOAGAAMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007091-A2 | HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2005-01-27 | — | — | WO | disclosed |