Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294446 | 1.00 | CACNA1G (0.45) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8294444 | 0.92 | CACNA1G (0.43) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8296252 | 0.78 | CACNA1G (0.46) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8296254 | 0.78 | CACNA1G (0.46) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8591058 | 0.70 | RPA1 (0.73) | MEN1KMT2AMDM2MCL1BCL2 | |
| SCHEMBL8591003 | 0.69 | CACNA1G (0.55) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8591001 | 0.69 | CACNA1G (0.55) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8590028 | 0.69 | PPP1CA (0.59) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8297233 | 0.68 | MDM2 (0.46) | CACNA1GCACNA1HMALT1MEN1KMT2A | |
| SCHEMBL8301692 | 0.66 | CACNA1G (0.49) | CACNA1GCACNA1HMALT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477049-B1 | Amido-3-pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 1999-12-01 | — | — | EP | claimed |