Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18938485 | 0.77 | GRIN2B (0.44) | CES2CES1ALDH1A1ALOX15GRIN2B | |
| SCHEMBL30605750 | 0.77 | GAA (0.50) | CES2CES1ALDH1A1ALOX15GRIN2D | |
| SCHEMBL102439 | 0.77 | GAA (0.50) | CES2CES1ALDH1A1ALOX15GRIN2D | |
| SCHEMBL102438 | 0.77 | GAA (0.50) | CES2CES1ALDH1A1ALOX15GRIN2D | |
| SCHEMBL22137160 | 0.76 | RAB9A (0.44) | ALDH1A1GAANPC1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL8561309 | 0.75 | CES2 (0.46) | CES2CES1ALDH1A1ALOX15GRIN2D | |
| SCHEMBL18940155 | 0.74 | BCAT2 (0.50) | CES2CES1ALDH1A1ALOX15GRIN2D | |
| SCHEMBL18938483 | 0.73 | CTSL (0.38) | CES2CES1ALDH1A1ALOX15GRIN2D | |
| SCHEMBL24801691 | 0.72 | LMNA (0.41) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL522903 | 0.72 | CES2 (0.52) | CES2CES1ALDH1A1ALOX15CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116548-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | Novartis AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2005014602-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |