Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350202 | 0.85 | CTSK (0.53) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5392135 | 0.84 | RAB9A (0.62) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5897928 | 0.82 | ADAM17 (0.58) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL8297367 | 0.80 | TAS1R3 (0.62) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL14193428 | 0.77 | CTSS (0.61) | RAB9ANPC1KMT2ASSTR3 | |
| SCHEMBL603555 | 0.75 | SSTR3 (0.52) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL1756678 | 0.75 | SSTR3 (0.52) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL8803719 | 0.75 | SSTR3 (0.52) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5032040 | 0.75 | SSTR3 (0.52) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL1727942 | 0.75 | SSTR3 (0.52) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106285-A1 | BENZAMIDE NITRILE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-12-09 | — | — | WO | disclosed |