SCHEMBL8369191

SCHEMBL8369191

C=CC(=O)NCc1cccc2c1S(=O)(=O)NC2=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.39
CA2 P00918 8/20 0.39
CA9 Q16790 8/20 0.39
CA7 P43166 5/20 0.39
CA1 P00915 4/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
BCHE P06276 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
TGM2 P21980 1/20 0.38
GAA P10253 1/20 0.32
BTK Q06187 1/20 0.32
FBP1 P09467 2/20 0.32
PDE4A P27815 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368219 0.81 CA12 (0.38) CA12CA2CA9CA7CA1
SCHEMBL82972 0.76 GABRA1 (0.45) CA12CA2CA9CA7CA1
SCHEMBL3807234 0.74 CA12 (0.46) CA12CA2CA9CA7CA1
SCHEMBL5093607 0.72 CA12 (0.45) CA12CA2CA9CA7CA1
SCHEMBL3806455 0.72 PTGER4 (0.47) CA12CA2CA9CA7CA1
SCHEMBL59858 0.72 TGM2 (0.55) KMT2ALMNATGM2GAAALDH1A1
SCHEMBL13440433 0.71 CA12 (0.46) CA12CA2CA9CA7CA1
SCHEMBL10741433 0.69 TYMS (0.43) CA12CA2CA9CA7CA1
SCHEMBL8764868 0.69 KMT2A (0.47) KMT2ALMNATGM2GAA
SCHEMBL529430 0.69 CA12 (0.43) CA12CA2CA9CA7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0731113-B1 Polymers and photosensitive compositions obtained therefrom AGFA GEVAERT AG (DE) 1999-01-13 EP disclosed
US-5700621-A COPOLYMER BINDER OF ACRYLAMIDE OR ALKYLACRYLAMIDE AND ACIDIC HYDROGEN ATOM CONTAINING UNIT DERIVED FROM SULFONIC, CARBOXYLIC, PHOSPHONIC, CARBOXIMIDES, SULFONAMIDES, SULFONIMIDES AND PHENOLS AGFA-GEVAERT AG (DE) 1997-12-23 US disclosed
EP-0731113-A2 Polymers and photosensitive compositions obtained therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1996-09-11 EP disclosed