Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830424 | 0.90 | CYP3A4 (0.33) | PDE2AIDO1CYP3A4CYP2D6 | |
| SCHEMBL829740 | 0.84 | — | — | |
| SCHEMBL829465 | 0.81 | MEN1 (0.35) | PDE2A | |
| SCHEMBL830864 | 0.78 | — | — | |
| SCHEMBL4597139 | 0.78 | PPARA (0.37) | PDE2AIDO1CYP3A4CYP2D6 | |
| SCHEMBL580069 | 0.77 | LIPG (0.33) | — | |
| SCHEMBL830877 | 0.76 | NR3C1 (0.31) | — | |
| SCHEMBL16648469 | 0.74 | PTGDR2 (0.34) | PDE2A | |
| SCHEMBL831060 | 0.74 | CXCR2 (0.34) | — | |
| SCHEMBL829803 | 0.73 | MEN1 (0.30) | IDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099807-B1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSEONICS INC (US) | 2014-01-01 | — | — | EP | disclosed |
| US-8143068-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-7851225-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| EP-2099807-A2 | OXIDATION RESISTANT INDICATOR MOLECULES | Sensors For Medicine And Science, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| WO-2008066921-A2 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | AOX1, GPX4, SQOR | PDE2A 4157/4885IDO1 2029/4885CYP3A4 393/4885 |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | AOX1, GPX4, SQOR | PDE2A 4157/4885IDO1 2029/4885CYP3A4 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.