Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102540 | 0.83 | ENPP2 (0.56) | ACHEALDH1A1ENPP2CA2LPL | |
| SCHEMBL29398358 | 0.83 | ENPP2 (0.56) | ACHEALDH1A1ENPP2CA2LPL | |
| SCHEMBL7183051 | 0.83 | ACHE (0.52) | ACHEALDH1A1MAPK1PARP1ENPP2 | |
| SCHEMBL1988863 | 0.79 | ACHE (0.48) | ACHEALDH1A1MAPK1PARP1ENPP2 | |
| SCHEMBL14330056 | 0.78 | ENPP2 (0.56) | ALDH1A1ENPP2CA2LPLLIPG | |
| Dimethylamine SCHEMBL3761544 | 0.77 | ENPP2 (0.50) | ACHEALDH1A1ENPP2CA2LPL | |
| SCHEMBL5384894 | 0.77 | ACHE (0.58) | ACHEALDH1A1MAPK1PARP1HTR3E | |
| SCHEMBL12270471 | 0.77 | ALDH1A1 (0.42) | ACHEALDH1A1MAPK1ENPP2CA2 | |
| SCHEMBL12270803 | 0.77 | TRPV6 (0.61) | ACHEALDH1A1ENPP2CA2LPL | |
| M-Xylene SCHEMBL2862054 | 0.76 | ACHE (0.75) | ACHEALDH1A1MAPK1PARP1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041904-A2 | INHIBITORS OF CORONAVIRUS PROTEASE AND METHODS OF USE THEREOF | FULCRUM PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |