Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 10/20 | 0.45 |
| ▸ | PDE2A | O00408 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727785 | 0.85 | CCNT1 (0.46) | TRPV3TRPV1MDM2 | |
| SCHEMBL27738470 | 0.85 | NTRK1 (0.48) | TRPV1NTRK1CCNCCDK8 | |
| SCHEMBL4729310 | 0.83 | CCNC (0.37) | NTRK1CCNCCDK8 | |
| SCHEMBL4727670 | 0.78 | AURKA (0.38) | TRPV3TRPV1 | |
| SCHEMBL4779880 | 0.77 | FAAH (0.49) | TRPV1 | |
| SCHEMBL4780128 | 0.76 | CCNT1 (0.43) | TRPV1AKT1NTRK1CCNCCDK8 | |
| SCHEMBL4728071 | 0.73 | USP1 (0.46) | CCNCCDK8 | |
| SCHEMBL4725583 | 0.73 | CCNT1 (0.41) | TRPV1 | |
| SCHEMBL8299228 | 0.72 | CA12 (0.43) | TRPV3PDE2AP2RX3 | |
| SCHEMBL4729366 | 0.72 | SLC10A1 (0.36) | CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |