Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399382 | 0.69 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7399380 | 0.69 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8303817 | 0.69 | KDM4E (0.40) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7788333 | 0.68 | DRD2 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8300039 | 0.68 | ITGB3 (0.40) | ITGB3ITGA2BCYP2C9GRIN2BCYP2D6 | |
| SCHEMBL7788361 | 0.68 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7788302 | 0.68 | ITGB3 (0.67) | ITGB3ITGA2B | |
| SCHEMBL8305336 | 0.67 | KDM4E (0.43) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8300676 | 0.66 | KDM4E (0.42) | ITGB3ITGA2BCYP2C9GRIN2BCYP2D6 | |
| SCHEMBL8300631 | 0.66 | GRIN2B (0.40) | ITGB3ITGA2BCYP2C9GRIN2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |