Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156992 | 0.81 | L3MBTL1 (0.40) | LMNAHSP90AA1 | |
| SCHEMBL7022114 | 0.77 | LMNA (0.38) | LMNA | |
| SCHEMBL29010220 | 0.75 | LMNA (0.41) | LMNAHSP90AA1 | |
| SCHEMBL13134317 | 0.72 | THRB (0.40) | LMNA | |
| SCHEMBL8300321 | 0.71 | LMNA (0.39) | LMNA | |
| SCHEMBL11666850 | 0.70 | GPR84 (0.41) | LMNA | |
| SCHEMBL8470578 | 0.70 | — | — | |
| SCHEMBL31061865 | 0.70 | — | — | |
| SCHEMBL11611749 | 0.70 | — | — | |
| SCHEMBL9278015 | 0.69 | KDM4E (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658913-A | THIOPYRAZINE DERIVATIVES; ENZYME INHIBITOR OF PHASE 1 REACTION TO PREVENT THE FORMATION OF ACTIVATED TOXIC INTERMEDIATE METABOLITES AND INDUCE PHASE LL CONJUGATION REACTIONS TO PROMOTE EXCRETION OF TOXICS | Kim, Nak Doo (KR) | 1997-08-19 | — | — | US | claimed |
| CN-1115981-A | New chemopreventive compounds and a preparation method and use thereof | WON KEUN CHUNG (KR) | 1996-01-31 | — | — | CN | claimed |
| EP-0674628-A1 | NEW CHEMOPREVENTIVE COMPOUNDS AND A PREPARATION METHOD AND USE THEREOF | Kim, Nak Doo (KR) | 1995-10-04 | — | — | EP | claimed |
| WO-1995011236-A1 | NEW CHEMOPREVENTIVE COMPOUNDS AND A PREPARATION METHOD AND USE THEREOF | CHUNG, WON, KEUN (KR) | 1995-04-27 | — | — | WO | claimed |
| EP-0674628-B1 | CHEMOPREVENTIVE COMPOUNDS AND A PREPARATION METHOD AND USE THEREOF | KIM NAK DOO (KR) | 1999-12-22 | — | — | EP | disclosed |
| US-5658913-A | THIOPYRAZINE DERIVATIVES; ENZYME INHIBITOR OF PHASE 1 REACTION TO PREVENT THE FORMATION OF ACTIVATED TOXIC INTERMEDIATE METABOLITES AND INDUCE PHASE LL CONJUGATION REACTIONS TO PROMOTE EXCRETION OF TOXICS | Kim, Nak Doo (KR) | 1997-08-19 | — | — | US | disclosed |
| EP-0674628-A1 | NEW CHEMOPREVENTIVE COMPOUNDS AND A PREPARATION METHOD AND USE THEREOF | Kim, Nak Doo (KR) | 1995-10-04 | — | — | EP | disclosed |
| WO-1995011236-A1 | NEW CHEMOPREVENTIVE COMPOUNDS AND A PREPARATION METHOD AND USE THEREOF | CHUNG, WON, KEUN (KR) | 1995-04-27 | — | — | WO | disclosed |