Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300512 | 0.76 | ACHE (0.37) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL8300800 | 0.74 | ACHE (0.40) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL2692039 | 0.69 | PPARG (0.53) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL8305889 | 0.68 | ACHE (0.37) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL4253889 | 0.68 | HSD17B10 (0.58) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL10718048 | 0.67 | HSD17B10 (0.60) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL6954317 | 0.67 | HSD17B10 (0.60) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL6954649 | 0.67 | HSD17B10 (0.60) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL4256521 | 0.67 | HSD17B10 (0.60) | ACHEPPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL6961928 | 0.66 | PPARG (0.59) | ACHEPPARGAGTR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936221-A1 | NOVEL 2,4-DIOXOPYRROLIDINE AND 2,4-DIOXOTETRAHYDROFURAN DERIVATIVES AND MEDICINES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | LEAD CHEMICAL COMPANY LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |