Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330503 | 0.69 | ACHE (0.38) | ACHEESR2PPARGAGTR1APLNR | |
| SCHEMBL8300801 | 0.68 | ACHE (0.41) | ACHEESR2PPARGAGTR1APLNR | |
| SCHEMBL5411252 | 0.68 | AGTR1 (0.43) | ACHEESR2PPARGAGTR1LTB4R2 | |
| SCHEMBL9402468 | 0.67 | ACHE (0.44) | ACHEESR2PPARGAGTR1LTB4R2 | |
| SCHEMBL8300512 | 0.67 | ACHE (0.37) | ACHEESR2PPARGAGTR1APLNR | |
| Decane SCHEMBL9620442 | 0.66 | ESR2 (0.53) | ACHEESR2PPARGAGTR1GRIA2 | |
| Octane SCHEMBL9620215 | 0.66 | ESR2 (0.53) | ACHEESR2PPARGAGTR1GRIA2 | |
| SCHEMBL7649207 | 0.66 | ACHE (0.47) | ACHEPPARGAGTR1LTB4R2APLNR | |
| SCHEMBL10589349 | 0.66 | PPARG (0.47) | ACHEESR2PPARGAGTR1GRIA2 | |
| SCHEMBL9682387 | 0.66 | AGTR1 (0.43) | ACHEESR2PPARGAGTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936221-A1 | NOVEL 2,4-DIOXOPYRROLIDINE AND 2,4-DIOXOTETRAHYDROFURAN DERIVATIVES AND MEDICINES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | LEAD CHEMICAL COMPANY LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |