Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301305 | 0.92 | CCR3 (0.51) | SIGMAR1ACHESLC2A1CCR3LMNA | |
| SCHEMBL8299951 | 0.78 | ACHE (0.57) | ACHELMNAMAPT | |
| SCHEMBL6659339 | 0.73 | SIGMAR1 (0.86) | SIGMAR1MC4RCCR3LMNA | |
| SCHEMBL5754715 | 0.72 | GAA (0.64) | SIGMAR1ACHEMC4RCCR3LMNA | |
| SCHEMBL6957735 | 0.72 | MC4R (0.65) | SIGMAR1MC4RCCR3LMNA | |
| SCHEMBL1752874 | 0.72 | ACHE (0.74) | ACHE | |
| SCHEMBL4389670 | 0.72 | KMT2A (0.55) | — | |
| SCHEMBL2489199 | 0.71 | SIGMAR1 (1.00) | SIGMAR1ACHEMC4RCCR3LMNA | |
| SCHEMBL1415730 | 0.71 | SIGMAR1 (1.00) | SIGMAR1ACHEMC4RCCR3LMNA | |
| SCHEMBL576868 | 0.71 | SIGMAR1 (1.00) | SIGMAR1ACHEMC4RCCR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |