Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301159 | 0.92 | SIGMAR1 (0.50) | CCR3SLC2A1SIGMAR1LMNAACHE | |
| SCHEMBL8299951 | 0.76 | ACHE (0.57) | HRH3KDM4ELMNAGAAKMT2A | |
| SCHEMBL6657455 | 0.74 | CCR3 (0.85) | CCR3SIGMAR1LMNAPOLB | |
| SCHEMBL6659913 | 0.74 | CCR3 (0.79) | CCR3SIGMAR1KDM4ELMNAPOLB | |
| SCHEMBL13140399 | 0.74 | CCR3 (0.63) | CCR3HTR7SIGMAR1LMNAPOLB | |
| SCHEMBL6657649 | 0.73 | CCR3 (0.82) | CCR3HTR7SIGMAR1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL10502885 | 0.73 | CCR3 (0.76) | CCR3SIGMAR1LMNAPOLB | |
| SCHEMBL6659339 | 0.71 | SIGMAR1 (0.86) | CCR3SIGMAR1LMNAPOLBKMT2A | |
| SCHEMBL19716910 | 0.71 | ALDH1A1 (0.67) | CCR3HTR7KMT2A | |
| SCHEMBL11801794 | 0.70 | CCR3 (0.89) | CCR3SIGMAR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |