SCHEMBL4389670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8304705	0.83	CHEK1 (0.45)	KMT2AMEN1KCNH3PDE10A
	SCHEMBL11188509	0.75	SMN1; SMN2 (0.46)	KMT2APOLBRAD52KCNH3
	SCHEMBL7284684	0.74	POLB (0.50)	KMT2APOLBRAD52PDE5AAPP
	SCHEMBL17134738	0.73	KDM4E (0.55)	KMT2AMEN1NPC1ATM
	SCHEMBL11788237	0.72	KCNH3 (0.61)	KMT2ARAD52MEN1PDE5AAPP
	SCHEMBL1562297	0.72	APP (0.59)	KMT2ARAD52PDE5AAPPKCNH3
	SCHEMBL3298289	0.72	KCNH3 (0.73)	KMT2APOLBRAD52APPKCNH3
	SCHEMBL31703859	0.72	KMT2A (0.50)	KMT2APOLBRAD52MEN1NPC1
	SCHEMBL8301159	0.72	SIGMAR1 (0.50)	—
	SCHEMBL13968056	0.72	KMT2A (0.66)	KMT2APOLBRAD52MEN1PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.