Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16261830 | 0.95 | APP (0.51) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL831493 | 0.91 | APP (0.51) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL13056613 | 0.90 | GAA (0.49) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL17083543 | 0.90 | LMNA (0.58) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL27483976 | 0.88 | CYP1A2 (0.59) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL16270203 | 0.87 | GAA (0.50) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL16270513 | 0.86 | APP (0.54) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL654389 | 0.85 | GAA (0.66) | SMN1; SMN2CYP1A2CYP3A4NPC1RAB9A | |
| SCHEMBL829668 | 0.85 | TDP1 (0.46) | SMN1; SMN2CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL8625200 | 0.84 | NPC1 (0.60) | CYP1A2CYP3A4CYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11116866-B2 | Multi-putty adhesive and cement compositions for tissue hemostasis, repair and reconstruction | ABYRX, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200061236-A1 | MULTI-PUTTY ADHESIVE AND CEMENT COMPOSITIONS FOR TISSUE HEMOSTASIS, REPAIR AND RECONSTRUCTION | ORTHOCON, INC. | 2020-02-27 | — | — | US | disclosed |
| US-20190099514-A1 | MULTI-PUTTY ADHESIVE AND CEMENT COMPOSITIONS FOR TISSUE HEMOSTASIS, REPAIR AND RECONSTRUCTION | ORTHOCON, INC. | 2019-04-04 | — | — | US | disclosed |
| US-20160250374-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ORTHOCON, INC. | 2016-09-01 | — | — | US | disclosed |
| US-20160250374-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ORTHOCON, INC. | 2016-09-01 | — | — | US | disclosed |
| US-9314547-B2 | Absorbable multi-putty bone cements and hemostatic compositions and methods of use | ABYRX INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9314547-B2 | Absorbable multi-putty bone cements and hemostatic compositions and methods of use | ABYRX INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20090060979-A1 | CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | BEZWADA BIOMEDICAL, LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090060979-A1 | CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | BEZWADA BIOMEDICAL, LLC | 2009-03-05 | — | — | US | disclosed |
| EP-1937182-A2 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | Bezwada Biomedical LLC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1931334-A2 | FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM | Bezwada Biomedical LLC (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007030538-A2 | FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007030538-A2 | FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007030464-A2 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | BEZWADA BIOMEDICAL LLC (US) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007030464-A2 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | BEZWADA BIOMEDICAL LLC (US) | 2007-03-15 | — | — | WO | disclosed |
| US-20060188547-A1 | Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices | BEZWADA BIOMEDICAL, LLC (US) | 2006-08-24 | — | — | US | disclosed |
| US-20060172983-A1 | Functionalized drugs and polymers derived therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | SMN1; SMN2 3337/4885CYP1A2 1323/4885CYP3A4 1200/4885 |
| US-20090060979-A1 | CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | GUSB, BMP2, APEH | SMN1; SMN2 4617/4885CYP1A2 749/4885CYP3A4 457/4885 |
| US-20060172983-A1 | Functionalized drugs and polymers derived therefrom | OGFR, LOX, OPRM1 | SMN1; SMN2 3370/4885CYP1A2 1930/4885CYP3A4 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.