Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439711 | 0.92 | ALDH1A1 (0.42) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8302742 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8306053 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8300946 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8306989 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8303213 | 0.79 | LMNA (0.46) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8307242 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8304839 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPK1MEN1KMT2AGAA | |
| SCHEMBL8304450 | 0.77 | CASP6 (0.47) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL8302750 | 0.69 | CASP6 (0.48) | ALDH1A1MAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | claimed |
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |