Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361514 | 0.85 | RXRA (0.34) | CES2RXRARXRBALDH1A1KDM4E | |
| SCHEMBL3023134 | 0.82 | CES2 (0.53) | CES2RXRARXRBALDH1A1KDM4E | |
| SCHEMBL8301631 | 0.82 | RXRA (0.47) | CES2RXRARXRBALDH1A1KDM4E | |
| SCHEMBL28226119 | 0.78 | CFTR (0.49) | CES2RXRARXRBALDH1A1KDM4E | |
| SCHEMBL20560372 | 0.77 | CES2 (0.43) | CES2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20560140 | 0.76 | CES2 (0.38) | CES2ALDH1A1LMNACES1 | |
| SCHEMBL10333746 | 0.75 | TP53 (0.44) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL5316664 | 0.75 | DUSP3 (0.48) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL424990 | 0.74 | RXRB (0.70) | CES2RXRARXRBALDH1A1KDM4E | |
| SCHEMBL18291815 | 0.74 | ALDH1A1 (0.56) | CES2RXRARXRBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998334-A | Pyrazole compounds, processes for their production and herbicides containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0900205-A1 | PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041106-A1 | PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA LTD. (JP) | 1997-11-06 | — | — | WO | disclosed |