Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31638075 | 0.84 | RAB9A (0.42) | ALOX15LMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL14484808 | 0.79 | MCL1 (0.54) | ALOX15PTPN7LMNATSHRHSD17B10 | |
| SCHEMBL29159363 | 0.78 | ALOX15 (0.46) | ALOX15PTPN7LMNATSHRHSD17B10 | |
| SCHEMBL2921165 | 0.78 | ALDH1A1 (0.40) | LMNATSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15552719 | 0.77 | MCL1 (0.53) | ALOX15PTPN7LMNATSHRHSD17B10 | |
| SCHEMBL16847718 | 0.77 | MAPT (0.50) | LMNATSHRHSD17B10MAPTL3MBTL1 | |
| SCHEMBL17963039 | 0.76 | LMNA (0.50) | ALOX15PTPN7LMNATSHRHSD17B10 | |
| SCHEMBL7425169 | 0.75 | ALOX15 (0.65) | ALOX15PTPN7LMNATSHRALDH1A1 | |
| SCHEMBL25213572 | 0.75 | PTPN7 (0.46) | ALOX15PTPN7LMNATSHRHSD17B10 | |
| SCHEMBL8302306 | 0.74 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096804-A1 | DIAZABICYCLONONENE AND TETRAHYDROPYRIDINE DERIVATIVES AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2004-11-11 | — | — | WO | disclosed |