Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6717933 | 0.89 | LTA4H (0.58) | MEN1KMT2ALTA4HNPC1RAB9A | |
| SCHEMBL7468687 | 0.83 | ALDH1A1 (0.53) | HDAC3HDAC1HDAC2NCOR2LTA4H | |
| SCHEMBL3635901 | 0.79 | LTA4H (0.56) | MEN1KMT2ALTA4HNPC1RAB9A | |
| SCHEMBL13726322 | 0.79 | LMNA (0.57) | MEN1KMT2ALTA4HNPC1HPGD | |
| SCHEMBL4278729 | 0.77 | HDAC3 (0.54) | HDAC3HDAC1HDAC2NCOR2LMNA | |
| SCHEMBL10888065 | 0.77 | HDAC6 (0.63) | HDAC3HDAC1HDAC2NPC1ADAMTS5 | |
| SCHEMBL31248371 | 0.75 | HDAC1 (0.52) | KMT2AHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL19488520 | 0.75 | LTA4H (0.43) | HDAC3HDAC1HDAC2NCOR2LTA4H | |
| SCHEMBL2834319 | 0.74 | HDAC3 (0.55) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL23099650 | 0.74 | KMT2A (0.47) | MEN1KMT2AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089915-A1 | PIPERAZINE DERIVATIVE RENIN INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |