Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435833 | 0.71 | KDM1A (0.37) | KDM1AS1PR1S1PR3RXRARXRB | |
| SCHEMBL194461 | 0.70 | NISCH (0.33) | KIF11NOS3NOS2NISCH | |
| SCHEMBL3597375 | 0.69 | RAB9A (0.41) | — | |
| SCHEMBL19258816 | 0.68 | NOS3 (0.52) | KDM1AS1PR1S1PR3RXRARXRB | |
| SCHEMBL30090584 | 0.67 | NPC1 (0.52) | KDM1ATDP1 | |
| SCHEMBL4577045 | 0.67 | NPC1 (0.52) | KDM1ATDP1 | |
| SCHEMBL2753599 | 0.67 | CTSS (0.41) | KDM1AS1PR1S1PR3RXRARXRB | |
| SCHEMBL4455134 | 0.67 | KMO (0.44) | KDM1AS1PR1S1PR3KMONOS3 | |
| SCHEMBL9482063 | 0.66 | RXRA (0.54) | S1PR1S1PR3RXRARXRBRXRG | |
| SCHEMBL990825 | 0.66 | CYP2A6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937051-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1998020003-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-14 | — | — | WO | claimed |
| EP-0937051-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020003-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |