Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307985 | 0.85 | DRD2 (0.34) | DRD2HTR1A | |
| SCHEMBL8306164 | 0.83 | DRD2 (0.33) | DRD2HTR1A | |
| SCHEMBL8304731 | 0.81 | — | — | |
| SCHEMBL8301928 | 0.79 | DRD2 (0.34) | DRD2HTR1A | |
| SCHEMBL8303695 | 0.79 | ALDH1A1 (0.34) | DRD2HTR1A | |
| SCHEMBL8301746 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL8301972 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL8304724 | 0.70 | DRD2 (0.34) | DRD2 | |
| SCHEMBL8307023 | 0.68 | DRD2 (0.38) | DRD2HTR1A | |
| SCHEMBL8302748 | 0.66 | DRD2 (0.39) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548254-B1 | 6- OR 7-(IMIDAZOLIDIN-2-YLIDENEAMINO)-1,4-BENZOXAZINES AS ALPHA ADRENERGIC AGENTS | ALLERGAN INC (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5091528-A | Antiglaucoma, antidiarrhea agents, diuretics, vasoconstrictors | ALLERGAN, INC. (US) | 1992-02-25 | — | — | US | disclosed |