Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503015 | 0.88 | GPR84 (0.47) | LTA4HPLA2G2ATRPM8GPR84L3MBTL1 | |
| SCHEMBL18702895 | 0.88 | GPR84 (0.47) | LTA4HPLA2G2ATRPM8GPR84L3MBTL1 | |
| SCHEMBL3621324 | 0.82 | LTA4H (0.46) | LTA4HPLA2G2ATRPM8L3MBTL1POLB | |
| SCHEMBL27527029 | 0.82 | LTA4H (0.46) | LTA4HPLA2G2ATRPM8L3MBTL1POLB | |
| SCHEMBL26913141 | 0.79 | RHEB (0.49) | LTA4HPLA2G2ATRPM8L3MBTL1POLB | |
| SCHEMBL8303620 | 0.79 | LTA4H (0.53) | LTA4HPLA2G2ATRPM8L3MBTL1BRD4 | |
| SCHEMBL8304176 | 0.78 | L3MBTL1 (0.48) | LTA4HPLA2G2ATRPM8L3MBTL1POLB | |
| SCHEMBL23887763 | 0.78 | LTA4H (0.54) | LTA4HPLA2G2ATRPM8L3MBTL1POLB | |
| SCHEMBL15826425 | 0.78 | P2RX7 (0.40) | GPR84L3MBTL1BRD4RAB9AMAPT | |
| SCHEMBL9749973 | 0.77 | LTA4H (0.68) | LTA4HPLA2G2ATRPM8BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-0469833-B1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY CO ELI (GB) | 1999-09-08 | — | — | EP | disclosed |
| CN-1040108-C | Pharmaceutical compounds | LILLY INDUSTRIES LTD (GB) | 1998-10-07 | — | — | CN | disclosed |
| US-5281593-A | Pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| CN-1061413-A | Medicinal compound | LILLY INDUSTRIES LTD (GB) | 1992-05-27 | — | — | CN | disclosed |
| EP-0469833-A1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |